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Some 2,000 scientists, including dozens of Nobel Prize winners, have signed an open letter warning that the U.S. lead in science is being "decimated" by the Trump administration's cuts to research.

Also: Amazon Studios' leader resigns after allegations of sexual harassment; Houston reservoirs finally release the last of hurricane floodwaters; and Chinese leaders hold a major congress.

Also: Thailand's ex-prime minister is sentenced to prison; rockets hit Kabul's airport after Mattis passes through; and rights groups claim the Saudi-led blockade is hurting Yemeni civilians.

Also: Peace envoy meets with Assad; woman in police uniform kills U.S. contractor in Kabul; snow could make post-Christmas travel tough in much of the nation; Sen. Mike Crapo, D-Idaho, faces drunk driving charge.

Also: Malala, Pakistani girl shot by Taliban, speaks out; Iran says Israel will regret strike on Syria; hostage situation continues in Alabama, where a 5-year-old boy has been held for almost a week.

Also: At least seven people died at site of Harlem explosion; two people were killed in Austin when a car plowed into SXSW crowd; and the Oscar Pistorius murder trial continues.

Also: Speculation mounts that San Diego mayor will soon step down; former Egyptian President Hosni Mubarak to be under house arrest after he's released from prison; Bradley Manning says "I am female"; and California kidnap victim Hannah Anderson talks about her ordeal.

Also: A former Playboy model alleges an affair with Donald Trump; a Maryland girl struck in a high school shooting is taken off life support; and the city of Atlanta's government computers are hacked.

Also: South Korean officials will brief the U.S. on their visit to North Korea; Singapore releases a report on a deadly 2017 U.S. warship accident; and Amazon's Alexa freaks people out by laughing.

Also: Blizzard conditions will strike parts of the northeast today; how the U.K. could punish Russia for its apparent use of a nerve agent; and UConn is the first women's NCAA basketball seed.